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Radiation therapy can disrupt the normal functioning of these cells, causing them to release an excess of inflammatory cytokines, thereby initiating an inflammatory cascade that results in neuronal tissue damage [182]

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Cytosolic Ca 2+ entering the mitochondrial matrix through the mitochondrial Ca 2+ uniporter (MCU) stimulates OXPHOS by activating pyruvate dehydrogenase phosphatase, which in turn, increases the activity of pyruvate dehydrogenase complex [21]

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Antimicrobials like berberine can kill both good and bad bacteria