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Sulfonylureas also require dose reduction or discontinuation

These effects were similar to those previously observed in MD-induced low-carnitine tilapia, zebrafish and rodents ( Reference Li, Li and Qin 32 , Reference Pan, Li and Li 34 , Reference Degrace, Demizieux and Gresti 52 ) , and indicate abnormal lipid metabolism as part of a metabolic syndrome

Unnikrishnan R, Anjana RM, Mohan V (2016) Diabetes mellitus and its complications in India

Use outside of clinical trials is illegal in many jurisdictions

Future research should consider composite strategies, such as microbiota-responsive or time-dependent coatings, to further refine pH-dependent release control and thereby improve formulation stability and strengthen the translational potential of this platform