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Nevertheless, future clinical randomized trial is warranted to determine the effectiveness of currently used therapies

In the nested case-control extension of the study, a history of acute pancreatitis was the only baseline variable found to predict postoperative acute pancreatitis

In additional secondary endpoints, retatrutide reduced known markers of cardiovascular risk, including non-HDL cholesterol, triglycerides, and high-sensitivity C-reactive protein (hsCRP), and at the highest dose lowered systolic blood pressure by 14.0 mmHg, using the efficacy estimand

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I'd rather not find out through my blood sugar that it was bad