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As research continues to reveal new applications and mechanistic insights, this compound stands poised to contribute to breakthrough discoveries across the expanding landscape of metabolic biology and translational research

However, our study size was small and its results need to be interpreted with caution

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Canagliflozin significantly inhibits inflammatory factor expression, including cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase, exerting cardioprotective effects by regulating inflammation and ferroptosis through the AMP-activated protein kinase (AMPK) pathway (83)