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The following list is not exhaustive, but summarizes the main families of molecules which can cross or not the BBB

Patients and prescribers should consider the individual's condition, the potential for systemic effects, and the availability of alternative treatments when deciding to use this formulation

That area is still developing, and findings vary across medications, populations, and study designs, so it is best treated as an emerging part of the picture rather than a settled explanation

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The induction or worsening of tinnitus by cochlear implants has also been reported