Proliferation of cancer cell is highly dependent on iron, and abnormal iron metabolism triggers an increase in susceptibility to ferroptosis ( 3.2 Lipid peroxidation Lipid peroxidation is one hallmark of ferroptosis, and also the basis for ferroptosis
Digestive conditions can do the same
The "minimal initial benefit" group (approximately 5-10% of users) reported limited improvements during treatment making discontinuation effects irrelevant, typically explained by inadequate product quality with degraded or low-concentration GHK-Cu, inappropriate application technique reducing absorption, unrealistic expectations exceeding what any topical can achieve, severe underlying pathology requiring medical intervention beyond cosmetic peptides, or individual non-responsiveness to copper peptide treatment for genetic or physiological reasons
doi: 10.1016/j.cld.2013.07.005
[DOI] [PubMed] [Google Scholar] 163.Zhang L., Liu J., Cheng C., Yuan Y., Yu B., Shen A., Yan M