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This work shows that AR blockade enhances the effectiveness of immune-checkpoint therapy in prostate cancer by preventing CD8 + T cell exhaustion and boosting IFN production

doi: 10.1007/s10067-014-2794-9 14 NadarajahNPramudyoR

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J Biol Chem (2007) 282:3010719.10.1074/jbc.M705325200 172 HarveyKFMattilaJSoferABennettFCRamseyMREllisenLWet alFOXO-regulated transcription restricts overgrowth of Tsc mutant organs