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Actually, the centrifugation process may be challenging since it may be ineffective to pellet the targeted vesicles at low speeds, and prolonged ultracentrifugation may produce impurities that are not vesicles and distort the size profiles (Rutter and Innes, 2020)

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Based on microarray studies we found that the antihormone resistant MCF-7:2A cells express markedly elevated levels of glutathione synthetase (GS) and glutathione peroxidase 2 (GPx2)