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5 Additionally, clinical trials have shown GLP-1 RAs to have beneficial effects on lipid profiles and blood pressure

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The article adds that metabolic stress from rapid loss can suppress gonadotropin-releasing hormone and disrupt pituitary-ovarian signaling, while shifts in ghrelin and satiety hormones may alter gonadotropin secretion

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The term incretin effect is used to describe the phenomenon that oral glucose induces a more robust insulin response than intravenous glucose administration