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McGuire, found that oral semaglutide reduced major adverse cardiovascular events (MACE) to 3.1 events per 100 person-years, compared to 3.7 events in the placebo group a 14% reduction (HR 0.86) over a median follow-up of 49.5 months

In the 1990s, researchers studying the Gila monster (Heloderma suspectum), a venomous lizard native to the southwestern United States and northwestern Mexico, made a groundbreaking discovery that would transform diabetes treatment

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Semaglutide acts on the pancreas to reduce both pre- and post-prandial blood glucose concentrations in a glucose-dependent manner primarily by increasing insulin production and inhibiting the secretion of glucagon