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In the ageing population, the ability to absorb B12 often declines, which can affect energy levels and cognitive function

34,552 UPS and autophagy: complementary degradation pathways The UPS and autophagy are the two primary protein degradation pathways in cells

Concentrations used for all compounds were tested for toxicity and effectiveness and chosen based on these results and doses were selected based on prior studies demonstrating immunomodulatory effects in vitro and in vivo without toxicity

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For control groups 36, we matched on all confounders but multiplied pre-exposure BMIs by fixed percentages to create counterfactual scenarios testing what would have happened if unexposed women had higher baseline BMIs