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But its gastrointestinal side effects (nausea, vomiting, diarrhea) can lead to dehydration, which can worsen existing kidney disease

Headache rates in SURPASS trials Across the SURPASS clinical trials, between 4% and 14% of participants reported headaches depending on the dose they received

To ensure safety, we align with recommendations from Dietary Guidelines for Americans, the American Medical Association, and the American Heart Association

To support chemist collaboration and ensure practical usability, we develop an interactive graphical user interface (GUI) that allows domain experts to visualize and intervene in retrosynthetic reasoning in real time

The greatest absolute risk reduction comes from improving very elevated glycaemic levels, and a more modest reduction results from near normalisation of plasma glucose levels [2, 14]