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Its main function is to act in the transport of long-chain fatty acids to the mitochondria to perform beta oxidation and, in addition, it is an important cofactor of peroxisomal oxidation [27]

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Interestingly, macrophage SR-BI has recently been shown to mediate efferocytosis (phagocytosis of dead cells) in the setting of atherosclerosis via a Src/Akt/Rac1 signaling pathway, reducing necrosis in lesions (185)

These can include unexpected fluctuations in blood sugar levels, gastrointestinal discomfort, or changes in appetite

These insights can help your provider tailor starting dose and titration pace, potentially reducing wasted spending on mismatched protocols and supporting faster route to an effective, affordable regimen