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Some flavors (like Pink Lemonade) use stevia and erythritol to reduce the sugar content, but consumers should be aware of which sweeteners are being used

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Specifically, mutagenesis of ECD, ECL1 and ECL3 individually increased the basal activity of GCGR, which could result from the interruption of intramolecular interactions between the ECD and ECL1/3 that otherwise stabilize the receptor in an inactive state

[PMC free article: PMC3758473] [PubMed: 18802415] 16