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4, 5 Among the growth factors involved in the proliferation step, hepatocyte growth factor (HGF), transforming growth factor alpha (TGF ) and epidermal growth factor (EGF) induce hepatocytes to override the mitogen restriction point located at 2/3 of G1 phase

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The researchers also found that weight-loss medication use was higher among women than men (4.0% versus 1.7%) and higher among those of middle age (4.2% of 45 and 55-year-olds compared to 1.2% of 18-year-olds and 1.5% of 75-year-olds)