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Structurally modified to reduce binding to IGF-binding proteins, IGF-1 LR3 may remain bioactive significantly longer than unmodified IGF-1 under experimental conditions, allowing for sustained receptor engagement and downstream pathway analysis

IGF-1 LR3 falls under the World Anti-Doping Agency's S2 category (peptide hormones, growth factors, related substances, and mimetics) and is prohibited at all times both in and out of competition

The peptides may also reportedly improve skin elasticity by promoting the synthesis of collagen

Yolland CO, et al

The table below summarizes how the three compare across the characteristics researchers look at most