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141 In an uncontrolled trial in 690 men diagnosed with infertility and found to have low sperm motility and high sperm DNA fragmentation, 14 weeks of supplementation with a combination of 400 IU vitamin E plus 200 mcg selenium daily improved sperm motility, morphology, or both, and resulted in a 10.8% pregnancy rate after 14 weeks

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Proposed Mechanistic Model of ALC in Depression and Stress-Related Modulation ALC may exert antidepressant effects through converging mechanisms including mitochondrial bioenergetic enhancement, epigenetic upregulation of mGlu2 expression, and reduction of neuroinflammation