Kalchhauser et al., 2011), a Cyclin-dependent kinase inhibitor that regulates cell cycle entry/exit decisions ( cki-2 partially rescues the germline stem cell depletion phenotype in fbf-1 fbf-2 double mutant adult hermaphrodites (Kalchhauser et al., 2011), suggesting that repression of cki-2 is not the only mechanism by which FBFs promote stem cell proliferation
One practical takeaway for me is that asking about GLP-1 use will increasingly become part of routine psychiatric assessment
Reuter S, Gupta SC, Chaturvedi MM, Aggarwal BB
Clinical trials have shown that liraglutide, the primary compound in GLP-1 medications, resulted in a 3.4% to 6.1% greater mean weight loss compared to placebo, with 50% to 73% of subjects achieving at least a 5% reduction in baseline body weight
Build a shake into a set time, like mid-morning