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In the current study, depriving RPE cells of the essential GSH precursor Cys 2 by culturing cells in Cys 2 -free culture medium or blocking de novo synthesis of GSH by using GCL inhibitor BSO or blocking Cys 2 uptake by pharmaceutical inhibition of system x c caused cell death

Lysov, F

However, as it assumes that the entire system is at a steady state, a simple MFA cannot simulate any temporal changes in metabolite concentrations

Peptides are essential signaling molecules involved in various physiological processes, including metabolism, reproduction, and immune responses

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