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The TRIUMPH-4 trial revealed a notable incidence of dysesthesia, an abnormal sensation affecting touch perception that can cause numbness, tingling, or unusual skin sensitivity

Metabolism 27 , 201208

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By blocking the effects of androgens, spironolactone helps reduce oil production, slow hair follicle miniaturisation, and improve unwanted hair growth. She adds that it isn't routinely prescribed to men because of those same anti-androgen effects, which can lead to side effects including breast enlargement, reduced libido and sexual dysfunction

sanfranciscensis recycles GSSG to GSH in wheat sourdough and thus maintains a high reduced thiol concentration [69]