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This may seem like a small step, but it can make a big difference in how painful the injection feels

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After 2 weeks of treatment, mice treated with GLP-1MK-801, as well as those subjected to calorie restriction or GLP-1 monotherapy, demonstrated enhanced glucose tolerance compared with mice that were treated with the vehicle or MK-801 monotherapy (Extended Data Fig

Obesity is a long-term medical condition, just like diabetes or high blood pressure, he says