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Esmaeilian Y, Hela F, Bildik G, et al

Cohen Y, Goldenberg-Cohen N, Akrish S, Shani T, Amariglio N, Dratviman-Storobinsky O, et al

Lifestyle measures, including physical activity and healthy eating, are vital. As with drugs for hypertension or high cholesterol, if you experience good results with no side effects, semaglutide may be prescribed until you reach your goal

Known adverse effect profile Gastrointestinal effects: Nausea represents the most common adverse effect, particularly during dose escalation

In a 48-week Phase 2 obesity trial, participants on the 12mg dose recorded a mean body-weight reduction of 24.2%, versus 2.1% on placebo[1]. 83% of that group lost 15% or more of their body weight, and 93% lost at least 10%[1]