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Cagrilintide had one of the lowest GI odds ratios among incretin-class compounds in a 2025 network meta-analysis, but combination GI burden has not been formally quantified

Diabet Med 24(4):333343 Scheen AJ (2023) Cardiovascular protection significantly depends on HbA1c improvement with GLP-1RAs but not with SGLT2 is in type 2 diabetes: a narrative review

While obesity and type 2 diabetes remain strong risk factors, MASLD also affects patients with normal BMI, a phenotype that is especially prevalent in Asian populations and increasingly recognized in broader practice

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