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Fibromyalgia is now widely recognised as a disorder affecting multiple systems in the body

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In young adolescents from the general population, we found increased anxiety and depressive symptoms, increased GSH-redox cycle regulation (e.g., increased GPx activity, strong correlation between GPx and Gred activity) as well as increased HPA-axis activity (e.g., increased cortisol/11-deoxycortisol) in females as compared to males

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Although the original study protocol used the terms 5-component nephropathy composite and acute renal failure, here, we rephrased these as 5-component kidney composite and acute kidney failure, in line with recent nomenclature guidance introduced since the writing of the protocol 53

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In addition, D-Trp 2P forms an edge-to-face packing with Trp 4P and establishes a stabilizing intramolecular hydrophobic network with the side-chain of Lys 6P (Fig

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