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As patients start eating slightly more normally again because they feel better, the slower gastric clearance creates more opportunity for reflux

Semaglutide can also support lean muscle preservation, a crucial factor for those incorporating strength training, as often seen in bodybuilding communities

Hyperphagia and related metabolic complications are major challenges in PWS

Even in year one, analysts expect orforglipron to reach $500 million in sales and serve 360,000 patients, helping the three-drug franchise deliver $25.7 billion in 2026 alone