GLP-1s have FDA-approved indications beyond obesity, including diabetes, sleep apnea, and long-term weight maintenanceWe also recognize that BMI is an imperfect tool designed for research, not individualized medical care, said Midi Health
However, its immunomodulatory properties and potential cardiovascular toxicity have constrained clinical development, highlighting the challenges of translating promising preclinical findings into safe and effective patient therapies (179, 183)
To reduce diarrhea, eat small, frequent, low-fat meals, stay well-hydrated with water and electrolyte solutions, avoid trigger foods like greasy or spicy items, and consider over-the-counter antidiarrheals like loperamide after consulting your healthcare provider
Report Summary The call for achieving representative diversity in clinical trials and development programs is not new and indeed dates back more than five decades in the United States but has been amplified over the course of the COVID-19 pandemic as the realities of disparities in health outcomes among diverse populations have become increasingly evident
Dopamine and drugs acting on dopamine receptors have long been known to have the potential to be proarrhythmic (Tisdale et al., 1995a, 1995b, 2020), although the incidence of dopamine-associated arrythmia is relatively low
