Dairy Intake and Brain Health in Aging [WWW Document], n.d
An in vitro study using GnRH neurons of adult male mice demonstrated that both GLP-1 and Ex4 might excite GnRH neurons, either directly or indirectly by modulating the nitric oxide (NO) and endocannabinoid pathways that control the presynaptic excitatory GABA-ergic inputs to GnRH neurons [36]
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Medical Perspective Dr
Our findings build upon preliminary animal studies showing that central administration of GLP-1RA medications impacts taste aversion to sweetness. This shifting taste sensitivity from semaglutide medications like Ozempic could be what helps control food intake, as a persons feelings toward certain foods (namely sweets) may shift from rewarding to neutral