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Description

Hypo methylation (methylation decreases with age) is seen in hepatocellular carcinoma, breast cancer, lung cancer, nasopharyngeal cancer, smooth muscle sarcoma, and neuroendocrine tumor

Lactate dehydrogenase B is required for the growth of KRAS-dependent lung adenocarcinomas

Available at: Last updated 8/31/2011

This finding could be explained by a competition among selenoproteins for available selenium in the form of selenocysteine required for biosynthesis of the selenoproteins and for the selenium-incorporation machinery