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Stay well hydrated from day one

Pharmacokinetics: Why They Matter for Switching Tirzepatide has a half-life of approximately 5 days, reaching steady state after 4 weeks of once-weekly dosing

If nausea persists, your PlexusDx clinician can recommend timing adjustments or dietary modifications to improve comfort while maintaining medication effectiveness

In the published Phase 2 obesity trial, average weight loss at 48 weeks was: In TRIUMPH-1, average weight loss at 80 weeks was: This means the average weight loss seen with higher-dose retatrutide in trials has been around 2428% over longer treatment periods