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Glucagon-like peptide type 1 receptor agonistsIncretin effect and systemic effects of glucagon-like peptide type 1 and its agonists The incretin effect describes the phenomenon whereby oral glucose elicits higher (23 times) insulin secretory responses than does intravenous glucose.25 This is due to incretin hormones, such as GLP-1 or glucose-dependent insulinotropic polypeptide, which stimulate insulin secretion in response to food intake

All dosing should be conducted strictly within an approved institutional research framework, with documented ethics sign-off and risk assessment in place before any vial is reconstituted

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