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The compound belongs to a class of regulatory glycoproteins involved in biological signalling systems that interact with members of the transforming growth factor-beta (TGF-) family

Despite such a likely connection, only one study to date has assessed differences in markers of oxidative damage in children affected with konzo, where increased levels of 8,12-iso-iPF2-VI isoprostane in affected children was associated with deficits in neurocognition, but not deficits in motor impairment 3

minutum strain GSMF2 to 2.29-fold for S

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This finding remained consistent across various subgroups, including patients with differing baseline comorbidities (T2DM only, obesity only, or T2DM with obesity), as well as across different follow-up periods (1, 2, or 3 years)