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[1] These symptoms typically occur because the gastrointestinal system has had time to readjust during the medication-free period, and reintroduction can trigger a renewed adaptation response

The survival probabilities derived from the results (i.e., hazard ratios [HRs]) of multivariable Cox proportional hazard model analyses with adjustment for imbalanced patient characteristics were used to estimate the NNT measures (Eq

Generally, the benefits can last from several days to a few weeks, and regular maintenance injections may be recommended for sustained results

Adjustments to dose, timing, or supportive strategies (such as better hydration and balanced nutrition) may help reduce symptoms

Cost and accessibility GLP-1RA is expensive, which limits its popularity in low-income countries and regions