In this study, we leveraged multiple public datasets with large HCC sample sizes to identify SLC25A39 as a key molecule in HCC, using a comprehensive analysis of next-generation sequencing, single-cell RNA sequencing (scRNA-seq), and spatial transcriptomics
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Finally, we noticed that in the internal part of the spheroid, there is a partial loss of cell-cell junctions (red arrow number 7), which is partially restored in the samples treated with Ferrostatin-1
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