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In some cases, referral to a specialist may be appropriatethis might include endocrinology for hormonal assessment, sexual health services, or psychological support services

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Any patient currently on tirzepatide 15 mg who wants to trial retatrutide should discontinue tirzepatide first, allow at least two weeks for GI recovery, and begin retatrutide at the 2 mg starting dose with standard titration [2][4]