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This is consistent with earlier research that reported NR in the intestines was slowly converted to NAM prior to absorption.[25] NR can increase levels of NAD + [62,63], but in a comparative study done in animals, all the niacins given (NR, NAM, and NA) served as precursors for liver NAD + production, each with differing speeds and effects on the liver NAD metabolome over 24 hours.[26] NAD + and NADH are also sold as NAD dietary supplements

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doi: 10.1007/s00125-023-05969-6 82 Sparre-UlrichAHSparre-UlrichAHGabeMNGasbjergLSChristiansenCBSvendsenBHartmannet al