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Verification with serum methylmalonic acid and/or serum homocysteine level may be necessary in asymptomatic patients with high-risk conditions, symptomatic patients with low-normal levels of vitamin B 12 (200 to 350 pg per mL), or symptomatic patients in whom vitamin B 12 deficiency is unlikely but must be excluded

The appearance of a pustular/papular rash associated with high levels of Vitamin B12 is well described in the medical literature even though the exact mechanism appears to be unknown

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While Adenosyl/Hydroxy B12 Liquid offers a powerful, targeted mechanism for supporting mitochondrial energy, scavenging toxic nitric oxide, and repairing damaged nerves, it is not a standalone cure

the tonicity of an aqueous solution of the water-soluble composition of the present invention should be within the tolerable range when administered and is adjusted, for example, by isotonizing agents such as sodium chloride and mannitol