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By neutralizing the reactive oxygen species that act as triggers for mast cell degranulation, glutathione helps stabilize these hyperactive immune cells, reducing the systemic flood of histamine and inflammatory cytokines

This bimodal behavior suggests that the binding of the respective ligand makes the protein take two distinct conformations throughout the MD simulation

Circ Res 68:6168 Hall ED, Detloff MR, Johnson K, Kupina NC (2004) Peroxynitrite-mediated protein nitration and lipid peroxidation in a mouse model of traumatic brain injury

Its key features are: * Sterility: Free from any microorganisms

These findings suggest that GSH provides a clue to finding a drug target or strategy to reduce antibiotic resistance in bacterial infections.