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In SURMOUNT-4, this produced a 14 percentage point rebound in body weight over 52 weeks (Aronne et al., JAMA 2024)

ZEPBOUND clinical studies in OSA (Study 5 and Study 6) did not include sufficient numbers of patients age 65 years or older to determine whether they respond differently from younger adult patients

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After you have reached your weight loss goal, the research strongly suggests that staying on medication at an effective dose is key to keeping weight off