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Supplementary Table 1 List of primer

However, several of these agents have already shown substantial glucose-lowering efficacy, and it is likely that increased energy expenditure and weight reduction are conferred by GCGR agonism, while GLP-1 receptor agonism suppresses endogenous glucagon secretion [37]

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Dulaglutide The GLP-1 analog component of dulaglutide , a once-weekly injectable GLP-1 receptor agonist administered subcutaneously, has 90% amino acid sequence identity to natural GLP-1 (737), but structural changes confer resistance to DPP-4

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