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This study had been registered in Chinese Clinical Trial Registry (No

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The lack of body fat stores loss may be explained by the 18% increase in body fat mass associated with CHO supplementation alone, noted in the control group [6]

Role of Mitochondrial Pyruvate Transport in Disease In animal studies, where the transport of pyruvate into the mitochondria via the MPC has been disrupted by gene deletion or by pharmacological inhibition, a beneficial effect is observed at the level of insulin resistance, blood glucose homeostasis, diabetes, and the development of metabolic dysfunction-associated steatohepatitis, MASH (commonly referred to as non-alcoholic steatohepatitis: NASH)