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Glutamine is imported into cancer cells via multiple transporters, including the Na + -dependent transporters, system ASC (alanine/serine/cysteine-preferring) that function as obligatory exchangers, and the Na + -coupled neutral amino acid transporters (SNATs), which belong to the SLC38 superfamily (Cha et al., 2018

Rather, they act as prostaglandin synthases whose product (prostaglandin D2) modulates the hosts immune response, or even act as a lens crystallins [44,45,48,56]

T2DM patients combined with MASLD appear to respond better to EX-BID or EX-QW compared to those without MASLD, resulting in greater benefits in terms of LFC and cardiometabolic improvement

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However, despite GLP-1 agonists higher efficacy, the higher cost makes them not cost-effective [61] in some analyses when compared to older, less expensive alternatives