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Transient water retention or peripheral edema during initial dosing

It should be noted, however, that ALDH1A1, but not CYP2E1, is a downstream target of NRF2, which was found to be activated in untreated GCLM KO mouse liver

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Stable in lyophilized form when stored correctly (cool, dry, dark environment)

Despite their advantages, CL methods are limited by relatively low quantum efficiency and structural constraints favoring easily oxidized compounds (Krzymiski et al., 2019), while fluorescence techniques require more complex instrumentation and are susceptible to interference from sample matrices (Barba et al., 2013)