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The LPL monomers observed with deoxycholate and heparin have a slightly higher molecular weight than LPL alone, this may be due to association with heparin or deoxycholate increasing the apparent molecular weight

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However, due to elevated liver enzymes seen in patients taking the drug during testing, Pfizer said it decided to shed the lotiglipron program and move forward with its twice-daily GLP-1 pill