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Gepants (CGRP Receptor Antagonists): Ubrogepant and Rimegepant are excellent first-line acute options, especially for patients with cardiovascular risk factors (ischemic heart disease, history of stroke) or those who experience a "triptan sensation." Ditans (5-HT1F Receptor Agonist): Lasmiditan is centrally active and lacks vasoconstrictive properties, making it highly effective but limited by central nervous system side effects (e.g., somnolence, driving restriction for 8 hours)

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[DOI] [PubMed] [Google Scholar] 11.Ammann R.W., Akovbiantz A., Largiader F., Schueler G