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Localization NPs were performed using a confocal laser scanning microscopy (LSM-880, ZEISS)

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In contrast to the membrane disruption of red blood cells and Heinz bodies formation in favism, G6PD deficiency causing jaundice is perhaps attributed to the disruption of oxidant-antioxidant balance, impaired recycling of peroxiredoxin 2, thus affecting bilirubin clearance

In this study, as amino acid precursors could be fed to improve concentrations of intracellular free l-cysteine, we resorted to overexpression of GK instead of loss-of-function mutations in GPR for accumulation of -glutamyl phosphate to strengthen the redirection of -glutamyl phosphate to GSH synthesis