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** Examples of relevant comorbidities include type 2 diabetes, pre-diabetes, asthma, polycystic ovary syndrome, acid reflux, sleep apnoea, depression, chronic back pain, gallbladder problems, high blood pressure and heart disease.

Rotating sites helps prevent skin irritation and a condition called lipodystrophy, which is a localized buildup or loss of fat tissue that can affect how well the medication is absorbed

The absence of dedicated clinical trials for compounded preparations reflects regulatory structure, not necessarily reduced efficacy

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