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The lipotropic agents enhance the liver's ability to process and export fat, but if you're eating at maintenance or surplus, there's no net fat mobilization to process

A medicine only helps if the patient actually takes it. When looking at the next research steps for elecoglipron, Carroll said he would like to see a phase 3 clinical trial involving thousands of patients over a year or more, to see where the blood-sugar and weight effects actually land and hold

and long-term metformin with gastrointestinal intolerance and B12 depletion

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Long-term metformin therapy and vitamin B12 deficiency: An association to bear in mind