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Additionally, like GLP-1, SR18 also engages with the residues of TM1, TM2, TM6, and TM7 of GLP-1R

The duration of follow-up varied across the studies, spanning from 12 to 48 months, with an average follow-up duration of 27.5 months

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(Primary completion November 2025, 68-week treatment period, 4mg/9mg/12mg dose arms

Axel Kleemann, Jrgen Engel, Bernd Kutscher, Dieter Reichert: Pharmaceutical Substances