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Research from the STEP 1 trial showed that nausea affected 44.2% of participants on the 2.4 mg maintenance dose, compared to 17.4% on placebo

Inspection of the trajectory of weight changes with time revealed that weight loss continued to progress in the CagriSema group up to the end of treatment at 32 weeks, whereas in the semaglutide and cagrinlitide groups, weight reduction seemed to approach a plateau [10]

As we explained in the proposed rule, we believe that having hospitals add their NPI(s) to the MRF would improve the comparability of HPT and other healthcare data, including health plan transparency data from the TiC MRFs

Also, heavy alcohol use can increase the risk of pancreatitis, which we want to avoid with these meds

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