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The pathophysiology of diabetes involves a defective amplification of the late-phase insulin response to glucose by glucose-dependent insulinotropic polypeptideRegardless of etiology and phenotype

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Enrollment growth has slowed somewhat (4% growth from 2024 to 2025), but MA remains on track to cover a majority of beneficiaries in coming years

The first-in-human Phase I clinical trial of JPH203 in patients with advanced solid tumors demonstrated improved therapeutic effects, particularly in two patients with CRC treated daily with intravenous JPH203 [73]

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